Sebacic Acid. Sebacic acid (CAS NO.111-20-6) is a low toxic substance, with flammability, burning will produce toxic fumes, so it should be stored in cool and dry environment, dry powder, foam, sand, carbon dioxide, water mist can be used if Abstract. It is resolved in ethanol, ether and soluble slightly in water. Sebacic acid is a derivative of castor oil. It is a white flake or powdered solid. Sebacic Acid is a white flake or powdered crystal. CopyCopied, CSID:5004, http://www.chemspider.com/Chemical-Structure.5004.html (accessed 23:35, Jan 8, 2021) The solubility of sebacic acid was found as 500 g L −1 in the optimum conditions at 400 K temperature, 4 min dynamic time and 28 min static time. However works on polyesters of sebacic acid are rare. Combustible. Applications Sebacic acid is used as a monomer for nylon 610, plasticizers, lubricants, hydraulic fluids, cosmetics and candles. 1272/2008 [CLP] Extra labelling to displayExtra classification(s) to display Lookchem Provide Cas No.17265-14-4 Basic information: Properties,Safety Data,Sds and Other Datebase. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. DESCRIPTION & APPLICATIONS Sebacic Acid is a white flake or powdered crystal. : Rinse cautiously with water for several minutes. Sebacic acid: ��ε�� ��������� 1,8 ... Foti, C.; Sammartano, S. Solubility and Activity Coefficients of Acidic and Basic Nonelectrolytes in Aqueous Salt Solutions. Degree of solubility in water: 1 g/l 20 °C: Solubility (very soluble in) Alcohol: An alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane. 111-20-6. Sebacic acid is also found in other lipids that coat the skin surface. 58 / Monday, March 26, 2012 / Rules and Regulations 10/12/2015 EN (English US) 2/5 First-aid Measures After Eye Contact: Rinse cautiously with water for several minutes. 58 / Monday, March 26, 2012 / Rules and Regulations 10/12/2015 EN (English US) 2/5 First-aid Measures After Eye Contact: Rinse cautiously with water for several minutes.Remove contact lenses, if present and It is a white flake or powdered solid. Solubilities of sebacic acid in binary ethanol + water solvent mixtures were measured by the dynamic method using a laser monitoring observation technique at a temperature range from (288 to 352) K. The mole fraction of ethanol in the solvent mixtures ranges from 0 to 1. Currently, SA is produced exclusively from alkaline pyrolysis of castor oil. C(CCCCC(=O)O)CCCC(=O)O Solubility Slightly soluble in water. In its pure state it is a white flake or powdered crystal. It is a white flake or powdered solid. Display Name: Sebacic acid EC Number: 203-845-5 EC Name: Sebacic acid CAS Number: 111-20-6 Molecular formula: C10H18O4 IUPAC Name: decanedioic acid Sebacic acid (8CI) Registration dossier . Other names. It is a waxy set of lipids composed of triglycerides (≈41%), wax esters (≈26%), squalene (≈12%), and free fatty acids (≈16%). Decanedioic acid sodium salt TOP1 supplier Cas No: 17265-14-4 USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. PubChem ChemSpider SMILES 3400 mg/kg (大鼠经口) [5] 6000 mg/kg (小鼠经口) [5] 若非注明，所有数据均出自一般条件（25 ，100 kPa）下。 It has wide industrial uses as a coolant, plasticizer, lubricant, hydraulic fluid, cosmetic, candle, and others. It is resolved in ethanol, ether and soluble slightly in water. Human neutrophils can convert sebacic acid to its 5-oxo analog, i.e.5-oxo-6E,8Z-octadecaenoic acid (5-oxo-ODE). One of the largest uses of Sebacic Acid is in the manufacture of Nylon 6-10. Other identifiers. Gujarat India. 77, No. Sebacic Acid Skin Not Available Eyes Not Available Respiratory LC50 Inhalation - rat - > 4,500 mg/m3 Ingestion Not Available Carcinogenicity IARC No components of this product present at levels greater than or equal to 0.1% is identified as probable, possible or ��� SEBACIC ACID FOR SYNTHESIS Safety Data Sheet www.lobachemie.com 09/04/2015 2/8 Adverse physicochemical, human health and environmental effects No additional information available 2.2. SEBACIC ACID 1 Physical and Chemical Fuction: Molecular Formula: HOOC(CH2)8COOH Molecular Weight: 202.25 It is white powder crystal, slightly dissolves in water, completely dissolved in ethanol or ether, but not in benzene. Safety Data Sheet (Sebacic Acid) DATE PREPARED: 1/20/2016 Page 6 of 6 Section 16. Sebacic acid 111-20-6 Sebacic acid 1,3,5-triazine-2,4,6-triamine salt 31970-90-8 Sebacic acid 1,3,5-triazine-2,4,6-triamine salt 94159-18-9 Sebacic acid 2,2',2''-nitrilotriethanol complex 94202-16-1 Sebacic acid 2,2',2 85030-06-4 Sebacic acid is normally made from castor oil, which is essentially glyceryl ricinoleate. To detect the synergistic effect, solubilities of sebacic acid in 14.35 %, 36.97 %, 79.81 %, and 90.00 % mole fraction ethanol aqueous solution were determined to supplement our previous report. An alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane. PGS has a linear degradation profile via surface erosion, is completely bioresorbable, and its macroporous structure is well suited for cellular infiltration, paracrine signaling, and neotissue formation.81,82 Chen and colleagues reported that the elastomeric properties of PGS scaffolds render it a promising implant for use in myocardial tissue engineering applications. �����щ�� ��ъ�⑹����� 留�寃� ��ъ�댄�몃�� ��ㅼ�������� ��ъ�⑹��媛� ��ъ�댄�몃�쇰낫��� ���������寃� ��댁�⑺�� ��� ������濡� 荑���ㅻ�� ��ъ�⑺�⑸�����. Sebacic acid is a naturally occurring dicarboxylic acid with the formula (CH2)8(CO2H)2. 2. Contact Supplier High quality Sebacic Acid Disodium Salt Supplier Sebacic acid Revision Date 18-Jan-2018 (Brachydanio rerio) Persistence and DegradabilitySoluble in water Persistence is unlikely based on information available. [2], It can also be obtained from decalin via the tertiary hydroperoxide, which gives cyclodecenone, a precursor to sebacic acid. Solubility in water: 0.25 g/L[1] 遺����援ъ“��� (HOOC)(CH2)8(COOH)��� ��댁�쇨린��곗�쇰�� ��쇳�댁�� ��곗��(���珥�瑜� 留���ㅻ�� 寃�)瑜� ��삵����� sebum������ ������������ sebacic acid濡� 紐�紐���������쇰ʼn �����댄��吏� ������ 寃���쇰�� �����ㅼ�� 遺�留���������대�� 誘몄�몃��吏���� 諛������������� ������. Sebacic Acid was named from the Latin sebaceus (tallow candle) or … In patients with multiple acyl-CoA-dehydrogenase deficiency (MADD), also known as glutaric aciduria type II (GAII), a group of metabolic disorders due to deficiency of either electron transfer flavoprotein or electron transfer flavoprotein ubiquinone oxidoreductase, biochemical data shows an increase in urine sebacic acid excretion. Sebacic Acid. We also Provide Trading Suppliers & Manufacture for 17265-14-4 SEBACIC ACID ��� Compared with short-chain aliphatic acid, sebacic acid is more suitable for the preparation of polyesters, as short-chain aliphatic acids always conduce to intramolecular condensation. It has wide industrial uses as a coolant, plasticizer, lubricant, hydraulic fluid, cosmetic, candle, and others. Property Value Probability; Human Intestinal Absorption + 0.5731: Blood Brain Barrier + 0.7397: Caco-2 permeable-0.6412: P-glycoprotein substrate and has antitumor activity. text.skipToContent text.skipToNavigation. Incompatible with strong oxidizingagents, bases, reducing agents. Herein, we present an e Solubility results of sebacic acid were observed to be highly correlated with quadratic model according to analysis of variance. Sebacic Acid PGS has a linear degradation profile via surface erosion, is completely bioresorbable, and its macroporous structure is well suited for cellular infiltration, paracrine signaling, and neotissue formation.81,82 Chen and colleagues reported that the elastomeric properties of PGS scaffolds render it a promising implant for use in myocardial tissue engineering applications. Sebacic acid is an alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane. It has a role as a human metabolite and a plant metabolite. 5-Oxo-ODE is a structural analog of 5-oxo-eicosatetraenoic acid and like this oxo-eicosatetraenoic acid is an exceptionally potent activator of eosinophils, monocytes, and other pro-inflammatory cells from humans and other species. [4][5] Included in the free fatty acid secretions in sebum are polyunsaturated fatty acids of which sebacic acid is a major component. Registrant / Supplier Registered Updated 3M Belgium BVBA/SPRL Hermeslaan 7 1831 Diegem Belgium 2016 [Confidential] ARKEMA CASDA 420 rue d'Estienne d'Orves 92700 Colombes France 2010 ARKEMA FRANCE 420 rue d'Estienne d'Orves 92700 COLOMBES France View information & documentation regarding Sebacic acid, including CAS, MSDS & more. Approximation models were employed for determining solubility of sebacic acid at elevated temperatures. Sebacic Acid Skin Not Available Eyes Not Available Respiratory LC50 Inhalation - rat - > 4,500 mg/m3 Ingestion Not Available Carcinogenicity IARC No components of this product present at levels greater than or equal to 0.1% [6], InChI=1S/C10H18O4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8H2,(H,11,12)(H,13,14), InChI=1/C10H18O4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8H2,(H,11,12)(H,13,14), Except where otherwise noted, data are given for materials in their, Ullmann's Encyclopedia of Industrial Chemistry, "Mammalian Wax Biosynthesis II: Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family", https://en.wikipedia.org/w/index.php?title=Sebacic_acid&oldid=999055436, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License, 131 to 134.5 °C (267.8 to 274.1 °F; 404.1 to 407.6 K), This page was last edited on 8 January 2021, at 07:53. 77, No. A process for preparing sebacic acid by reacting in a first step (i) linoleic acid with water catalyzed by an oleate hydratase to form 10-hydroxy-12-octadecenoic acid, … Sebacic acid is normally made from castor oil, which is essentially glyceryl ricinoleate. SEBACIC ACID reacts exothermically to neutralize bases, both organic and inorganic. Main Use: Sebacic acid is a normal urinary acid. CopyCopied, Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, Predicted data is generated using the US Environmental Protection Agency’s EPISuite™, Click to predict properties on the Chemicalize site, For medical information relating to Covid-19, please consult the, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:41865, ACD/Labs Percepta Platform - PhysChem Module, US Environmental Protection Agency’s EPISuite™, Compounds with the same molecular formula, Search Google for structures with same skeleton, 295 deg C / 100 mm (400.5825 °C / 760 mmHg), 295 °C / 100 mm (400.5825 °C / 760 mmHg), 294.5 °C / 100 mmHg (399.9979 °C / 760 mmHg). In 95 % ethanol ( 100ml ) is 11.7g environmental effects No additional available. 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